The Lead
An HRS member-led journal review podcast bringing you the latest EP updates on the go
The Lead is a weekly journal review podcast designed to keep you updated and informed on the EP field's latest publications and hottest topics. Key takeaways, in-depth interpretations, and informative interviews are all fitted into 15-minute time slots so that they fit easily into your busy schedule.
ACE credit is available for most episodes of The Lead. It’s a convenient and affordable way to earn credits!
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Season Two Episodes (2024)
Episode 85: A Discussion of Bipolar Radiofrequency Ablation of Refractory Ventricular Arrhythmias, Results from a Multi-Centre Network
Discussion Topic: Bipolar Radiofrequency Ablation of Refractory Ventricular Arrhythmias, Results from a Multi-Centre Network
Host: Michael S. Lloyd, MD, FHRS
Guests: Jason T. Jacobson, MD, FHRS and Wendy S. Tzou, MD, FHRS
Speaker and Article Information: Download
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Episode 84: A Discussion of Arrhythmic Prognosis According to Left Ventricular Systolic Dysfunction Severity in Cardiac Sarcoidosis
Discussion Topic: Arrhythmic Prognosis According to Left Ventricular Systolic Dysfunction Severity in Cardiac Sarcoidosis
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Jordana Kron, MD and Edoardo Bressi, MD
Speaker and Article Information: Download
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Episode 83: A Discussion of Artificial Intelligence Age Prediction Using Electrocardiogram Data: Exploring Biological Age Differences
Discussion Topic: Artificial Intelligence Age Prediction Using Electrocardiogram Data: Exploring Biological Age Differences
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Tina Baykaner, MD, MPH and Janet K. Han, MD, FHRS
Speaker and Article Information: Download
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Episode 82: A Discussion of Conduction System Pacing Compared to Biventricular Pacing for Cardiac Resynchronization Therapy in Patients with Heart Failure and Mildly Reduced Left Ventricular Ejection Fraction: Results from the International Collaborative Left Bundle Branch Area Pacing Study (I-CLAS Group)
Discussion Topic: Conduction System Pacing Compared to Biventricular Pacing for Cardiac Resynchronization Therapy in Patients with Heart Failure and Mildly Reduced Left Ventricular Ejection Fraction: Results from the International Collaborative Left Bundle Branch Area Pacing Study (I-CLAS Group)
Host: Jason T. Jacobson, MD, FHRS
Guests: T. Jared Bunch, MD, FHRS and Dominik K Linz, MD, PhD
Speaker and Article Information: Download
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Episode 81: A Discussion of Specific Locations of Myocardial Inflammation and Fibrosis are Associated with Higher Risk of Events in Cardiac Sarcoidosis
Discussion Topic: Specific Locations of Myocardial Inflammation and Fibrosis are Associated with Higher Risk of Events in Cardiac Sarcoidosis
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Sanjay Divakaran, MD, MPH and Xiaoxiao Qian, MD
Speaker and Article Information: Download
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Episode 80: A Discussion of Catheter Ablation versus Advanced Therapy for Patients with Severe Heart Failure and Ventricular Electrical Storm
Discussion Topic: Catheter Ablation versus Advanced Therapy for Patients with Severe Heart Failure and Ventricular Electrical Storm
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Akshay Suvas Desai, MD, MPH and Robert N Kerley, MBChB
Speaker and Article Information: Download
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Episode 79: A Discussion of Managing Data Overload: AI Wearables and Apps (Recorded live at HRX in Atlanta)
Discussion Topic: Managing Data Overload: AI Wearables and Apps
Host: Deepthy Varghese, MSN, ACNP, FNP
Guest: Hawkins Gay, MD, MPH
Speaker and Article Information: Download
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Episode 78: A Discussion of The Potential of AI to Revolutionize Healthcare Delivery Research and Education in Cardiac EP & Understanding AI Biases in Clinical Practice (Recorded live at HRX in Atlanta)
Discussion Topics:
*The Potential of AI to Revolutionize Healthcare Delivery Research and Education in Cardiac EP
*Understanding AI Biases in Clinical Practice
Host: Deepthy Varghese, MSN, ACNP, FNP
Guest: Sana M. Al-Khatib, MD, MHS, FHRS
Speaker and Article Information: Download
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Episode 77: A Discussion of Pulmonary Vein Isolation vs Sham Intervention in Symptomatic Atrial Fibrillation (Recorded live at HRX in Atlanta)
Discussion Topic: Pulmonary Vein Isolation vs Sham Intervention in Symptomatic Atrial Fibrillation
Host: Janice Y. Chyou, MD, FHRS
Guests: Christopher C Cheung, MD, MPH and Prashanthan Sanders, MBBS, PhD, FHRS
Speaker and Article Information: Download
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Episode 76: A Discussion of Asundexian versus Apixaban in Patients with Atrial Fibrillation (Recorded live at HRX in Atlanta)
Discussion Topic: Asundexian versus Apixaban in Patients with Atrial Fibrillation
Host: Melissa E. Middeldorp, MPH, PhD
Guests: Christopher C Cheung, MD, MPH and Prashanthan Sanders, MBBS, PhD, FHRS
Speaker and Article Information: Download
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Episode 75: A Discussion of Pulmonary Vein Isolation With or Without Left Atrial Appendage Ligation in Atrial Fibrillation: The aMAZE Randomized Clinical Trial
Discussion Topic: Pulmonary Vein Isolation With or Without Left Atrial Appendage Ligation in Atrial Fibrillation: The aMAZE Randomized Clinical Trial
Host: Michael S. Lloyd, MD, FHRS
Guests: Lucas V. A. Boersma, MD, PhD and Michael Hoskins, MD
Speaker and Article Information: Download
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Episode 74: A Discussion of Incidence and patterns of atrial fibrillation after catheter ablation of typical atrial flutter—the FLUTFIB study
Discussion Topic: Incidence and patterns of atrial fibrillation after catheter ablation of typical atrial flutter—the FLUTFIB study
Host: Niraj Sharma, MD, FHRS
Guests: Rhea Pimentel, BChir, MD, FHRS and Usman Siddiqui, MD
Speaker and Article Information: Download
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Episode 73: A Discussion of Time to Benefit and Harm of Direct Oral Anticoagulants in Device-Detected Atrial Fibrillation: A Pooled Analysis of the NOAH-AFNET 6 and ARTESiA Trials
Discussion Topic: Time to Benefit and Harm of Direct Oral Anticoagulants in Device-Detected Atrial Fibrillation: A Pooled Analysis of the NOAH-AFNET 6 and ARTESiA Trials
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Rod S. Passman, MD, FHRS and Graham Peigh, MD, MS
Speaker and Article Information: Download
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Episode 72: A Discussion of The Predictive Value of PRECISE-DAPT Scores for Thrombogenic Milieu of the Left Atrium in Patients Awaiting AF Ablation
Discussion Topic: The Predictive Value of PRECISE-DAPT Scores for Thrombogenic Milieu of the Left Atrium in Patients Awaiting AF Ablation
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Hung-Fat Tse, Sr., MD and Glenn Young, MBBS
Speaker and Article Information: Download
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Episode 71: A Discussion of Fascicular Substrate Modification to Treat Human Ventricular Fibrillation
Discussion Topic: Fascicular Substrate Modification to Treat Human Ventricular Fibrillation
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Andrés Felipe Miranda-Arboleda, MD and Babak Nazer, MD
Speaker and Article Information: Download
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Episode 70: A Discussion of the 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation
Discussion Topic: The 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation
Host: Michael S. Lloyd, MD, FHRS
Guests: Jayanthi N. Koneru, MBBS, FHRS, and S. Patrick Whalen, MD, FHRS
Speaker and Article Information: Download
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Episode 69: A Discussion of Effect of Carvedilol vs Metoprolol on Atrial and Ventricular Arrhythmias Among Implantable Cardioverter-Defibrillator Recipients
Discussion Topic: Effect of Carvedilol vs Metoprolol on Atrial and Ventricular Arrhythmias Among Implantable Cardioverter-Defibrillator Recipients
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Sirena Bridges, MSN, FNP-BC, CCDS and Jodie L. Hurwitz, MD, FHRS
Speaker and Article Information: Download
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Episode 68: A Discussion of Ischemia-Induced Ventricular Proarrhythmia and Cardiovascular Autonomic Dysreflexia after Cardioneuroablation
Discussion Topic: Ischemia-Induced Ventricular Proarrhythmia and Cardiovascular Autonomic Dysreflexia after Cardioneuroablation
Host: Jason T. Jacobson, MD, FHRS
Guests: JC C Pachon-M, MD, PhD and and Sunny S. Po, MD, PhD, FHRS
Speaker and Article Information: Download
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Episode 67: A Discussion of Optimizing Patient Selection for Primary Prevention Implantable Cardioverter-Defibrillator Implantation: Utilizing Multimodal Machine Learning to Assess Risk of Implantable Cardioverter-Defibrillator Non-Benefit
Discussion Topic: Optimizing patient selection for primary prevention implantable cardioverter-defibrillator implantation: utilizing multimodal machine learning to assess risk of implantable cardioverter-defibrillator non-benefit
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Tina Baykaner, MD, MPH and Gurukripa N Kowlgi, MBBS, MSci
Speaker and Article Information: Download
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Episode 66: A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Complex Suppression in Nonischemic Cardiomyopathy With Implantable Cardioverter-Defibrillators
Discussion Topic: Class 1C Antiarrhythmics for Premature Ventricular Complex Suppression in Nonischemic Cardiomyopathy With Implantable Cardioverter-Defibrillators
Host: William Sauer, MD, FHRS, CCDS
Guests: Edward Gerstenfeld, MD, MS, FHRS & Yasser Rodriguez, MBA, MD
Speaker and Article Information: Download
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Episode 65: A Discussion of QRS Morphology and the Risk of Ventricular Tachyarrhythmia in Cardiac Resynchronization Therapy Recipients
Discussion Topic: QRS Morphology and the Risk of Ventricular Tachyarrhythmia in Cardiac Resynchronization Therapy Recipients
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: James O'Hara, PhD, PA and Shunmuga Sundaram Ponnusamy, MBBS, MD, CEPS-A
Speaker and Article Information: Download
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Episode 64: A Discussion of Leadless Pacemakers at 5-Year Follow-Up: the Micra Transcatheter Pacing System Post-Approval Registry
Discussion Topic: Leadless Pacemakers at 5-Year Follow-Up: the Micra Transcatheter Pacing System Post-Approval Registry
Host: Danesh Kella, MBBS, FHRS
Guests: Michael S. Lloyd, MD, FHRS and Siva K. Mulpuru, MD, FHRS
Speaker and Article Information: Download
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Episode 63: A Discussion of Antenatal Therapy for Fetal Supraventricular Tachyarrhythmias: Multicenter Trial
Discussion Topic: Antenatal Therapy for Fetal Supraventricular Tachyarrhythmias: Multicenter Trial
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Aarti Dalal, DO, FHRS, CEPS-P and Peter S. Fischbach, MA, MD
Speaker and Article Information: Download
Visual Aid: Download
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Episode 62: The Lead Live in Boston (A Triple Header!)
Discussion Topics:
Transvenous Extraction of Conduction System Pacing Leads: An International Multicenter (TECSPAM) Study
Safety, Efficacy, and Reliability Evaluation of a Novel Small-Diameter Defibrillation Lead: Global LEADR Pivotal Trial Results
Tachycardia Therapy and Endpoint Results of the First Modular, Intra-Body, Communicating, Subcutaneous Defibrillator-Leadless Pacemaker System: MODULAR ATP Interim Cohort
Hosts: Christopher Cheung, MD, MPH, Danesh Kella, MBBS, FHRS, and Deepthy Varghese, MSN, ACNP, FNP
Guests: Anish K. Amin, MD, FHRS, Mihail G. Chelu, MD, PhD, FHRS, Miguel A. Leal, MD, FHRS, Rajeev Kumar Pathak, MBBS, PhD, FHRS, Christopher Aldo A. Rinaldi, MBBS, MD. FHRS, Emily P. Zeitler, MD, MHS, FHRS
Speaker and Article Information: Download
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Episode 61: A Discussion of Impact of Atrial Fibrillation Burden on Health Care Costs and Utilization
Discussion Topic: Impact of Atrial Fibrillation Burden on Health Care Costs and Utilization
Host: Bruce Koplan, MD, MPH, FHRS
Guests: Matthew R. Reynolds, MD, MS, FHRS and Esseim Sharma, MD
Speaker and Article Information: Download
Visual Aid: Download
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Episode 60: A Discussion of Safety and Efficacy of Combining Left Atrial Appendage Occlusion With Another Cardiac Procedure
Discussion Topic: Safety and Efficacy of Combining Left Atrial Appendage Occlusion With Another Cardiac Procedure
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Shephal K Doshi, MD and Devi G. Nair, MD, FHRS
Speaker and Article Information: Download
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Episode 59: A Discussion of Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 ARTESiA Trials
Discussion Topic: Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 ARTESiA Trials
Host: Jason T. Jacobson, MD, FHRS
Guests: William H. Sauer, MD, FHRS, CCDS and Christian Thomas Ruff, MD
Speaker and Article Information: Download
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Episode 58: A Discussion of Atrial Fibrillation Progression after Cryoablation versus Radiofrequency Ablation: The CIRCA-DOSE Trial
Discussion Topic: Atrial Fibrillation Progression after Cryoablation versus Radiofrequency Ablation: The CIRCA-DOSE Trial
Host: Janice Y. Chyou, MD, FHRS
Guests: Fred M. Kusumoto, MD, FHRS and Julia H. Indik, MD, PhD, FHRS
Speaker and Article Information: Download
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Episode 57: A Discussion of EsophAguS Deviation During RadiofrequencY Ablation of Atrial Fibrillation: The EASY AF Trial
Discussion Topic: EsophAguS Deviation During RadiofrequencY Ablation of Atrial Fibrillation: The EASY AF Trial
Host: Michael S. Lloyd, MD, FHRS
Guests: Christopher R. Ellis, MD, FHRS and Stacy B. Westerman, MD, MPH
Speaker and Article Information: Download
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Episode 56: A Discussion of Durability of Pulmonary Vein Isolation Using Pulsed-Field Ablation
Discussion Topic: Durability of Pulmonary Vein Isolation Using Pulsed Field Ablation
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Amin Al-Ahmad, MD, FHRS, CCDS and Jorge Romero, Jr., MD, FHRS
Speaker and Article Information: Download
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Episode 55: A Discussion of Dynamic Electrocardiogram Changes are a Novel Risk Marker for Sudden Cardiac Death
Discussion Topic: Dynamic Electrocardiogram Changes are a Novel Risk Marker for Sudden Cardiac Death
Host: Janice Y. Chyou, MD, FHRS
Guests: Christine M. Albert, MD, MPH, FHRS and Marina Cerrone, MD
Speaker and Article Information: Download
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Episode 54: A Discussion of Development and Validation of the DOAC Score: A Novel Bleeding Risk Prediction Tool for Patients with Atrial Fibrillation on Direct-Acting Oral Anti-Coagulants
Discussion Topic: Development and Validation of the DOAC Score: A Novel Bleeding Risk Prediction Tool for Patients with Atrial Fibrillation on Direct-Acting Oral Anti-Coagulants
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Gregory Lip, MD and Elaine Y. Wan, MD, FHRS
Speaker and Article Information: Download
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Episode 53: A Discussion of Long-Term Outcomes of Resynchronization-Defibrillation for Heart Failure
Discussion Topic: Long-Term Outcomes of Resynchronization-Defibrillation for Heart Failure
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Akshay Suvas Desai, MD, MPH and Sunil Kapur, MD
Speaker and Article Information: Download
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Episode 52: A Discussion of Retrieval of Chronically Implanted Dual-Chamber Leadless Pacemakers in an Ovine Model
Discussion Topic: Retrieval of Chronically Implanted Dual-Chamber Leadless Pacemakers in an Ovine Model
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Mikhael F. El-Chami, MD, FHRS and Rohit Mehta, MD, FHRS
Speaker and Article Information: Download
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Episode 51: A Discussion of Omnipolar versus Bipolar Mapping to Guide Ventricular Tachycardia Ablation
Discussion Topic: Omnipolar versus Bipolar Mapping to Guide Ventricular Tachycardia Ablation
Host: Jason T. Jacobson, MD, FHRS
Guests: Isabel Deisenhofer, MD, FHRS, and Jeffrey R. Winterfield, MD, FHRS
Speaker and Article Information: Download
Visual Aid: Download
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Episode 50: A Discussion of New-Onset Atrial Fibrillation Prediction: the HARMS2-AF Risk Score
Discussion Topic: New-Onset Atrial Fibrillation Prediction: the HARMS2-AF Risk Score
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Sandeep K. Goyal, MD, FHRS and Andrea M. Russo, MD, FHRS
Speaker and Article Information: Download
Visual Aid: Download
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Episode 49: A Discussion of Stroke and Bleeding Risks of Endocardial Ablation for Ventricular Arrhythmias
Discussion Topic: Stroke and Bleeding Risks of Endocardial Ablation for Ventricular Arrhythmias
Host: William H. Sauer, MD, FHRS, CCDS
Guests: Uyanga Batnyam, MD and Usha B. Tedrow, MD, MS, FHRS
Speaker and Article Information: Download
Visual Aid: Download
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Episode 48: A Discussion of Influence of Monitoring and Atrial Arrhythmia Burden on Quality of Life and Health Care Utilization in Patients Undergoing Pulsed Field Ablation: A Secondary Analysis of the PULSED AF Trial
Discussion Topic: Influence of Monitoring and Atrial Arrhythmia Burden on Quality of Life and Health Care Utilization in Patients Undergoing Pulsed Field Ablation: A Secondary Analysis of the PULSED AF Trial
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Sammy Khatib, MD and William Whang, MD, FHRS
Speaker and Article Information: Download
Visual Aid: Download
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Episode 47: A Discussion of Multicenter Retrospective Evaluation of Magnetic Resonance Imaging in Pediatric and Congenital Heart Disease Patients with Cardiac Implantable Electronic Devices
Discussion Topic: Multicenter Retrospective Evaluation of Magnetic Resonance Imaging in Pediatric and Congenital Heart Disease Patients with Cardiac Implantable Electronic Devices
Host: Peter F. Aziz, MD, FHRS, CEPS-P
Guests: David Bradley, MD, FHRS, CEPS-P and Henry Chubb, MA, MBBS, PhD, FHRS, CEPS-P
Speaker and Article Information: Download
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Episode 46: A Discussion of Detecting Paroxysmal Atrial Fibrillation from an Electrocardiogram in Sinus Rhythm: External Validation of the AI Approach
Discussion Topic: Detecting Paroxysmal Atrial Fibrillation from an Electrocardiogram in Sinus Rhythm: External Validation of the AI Approach
Host: Deepthy Varghese, MSN, ACNP, FNP
Guests: Hawkins Gay, MD, MPH and Matthew Kalscheur, MD
Speaker and Article Information: Download
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Episode 45: A Discussion of 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation...
Discussion Topic: 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation...
Host: Michael S. Lloyd, MD, FHRS
Guests: Faisal M. Merchant, MD, FHRS and David Duncker, MD, FHRS
Speaker and Article Information: Download
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Episode 44: A Discussion of Intracardiac versus Transesophageal Echocardiography for Left Atrial Appendance Occlusion with Watchman FLX in the U.S.
Discussion Topic: Intracardiac versus Transesophageal Echocardiography for Left Atrial Appendance Occlusion with Watchman FLX in the U.S.
Host: William H. Sauer, MD, FHRS, CCDS
Guests: David Chang, MD and Sunil Kapur, MD
Speaker and Article Information: Download
Visual Aid: Download
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Episode 43: A Discussion of Implantable Subcutaneous Cardioverter-Defibrillators in Patients with Congenital Heart Disease
Discussion Topic: Implantable Subcutaneous Cardioverter-Defibrillators in Patients with Congenital Heart Disease
Host: Peter F. Aziz, MD, FHRS, CEPS-P
Guests: Maully J. Shah, MBBS, FACC, FHRS, CCDS, CEPS and Johannes von Alvensleben, MD
Speaker and Article Information: Download
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